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A lot has been learnt about cell adaptation and reaction from the experiments performed on many different cell types flown to space. Combinatorial treatments with 3,4-DAP and VGCC agonists proved synergistic in restoring suprathreshold endplate potentials in mouse diaphragms fully intoxicated by BoNT/A.
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Patients also display cognitive deficits including impairments in working memory, but a mechanistic link between thalamo-prefrontal circuit function and working memory is missing. Furthermore, a positive association was observed for the 6 most commonly used antimicrobials.